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US 2026/0077053 A1Published application
Antibodies and enonomers
AssigneeEnosi Therapeutics Corporation
InventorH. Michael Shepard
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Abstract
The subject invention provides a composition comprising an enomomer which comprises a) a carrier molecule, and b) at least one aptamer, wherein the carrier molecule is an antibody, an antigen-binding moiety, a serum protein, an intracellular protein, a messenger RNA (mRNA) or human serum albumin.
Claims19
A composition, comprising an enonomer, wherein the enonomer comprises:
- a) a carrier molecule, and
- b) at least one aptamer, wherein:
- the carrier molecule is an antibody, an antigen-binding moiety, a serum protein, an intracellular protein, a messenger RNA (mRNA), or human serum albumin;
- the half-life of the enonomer is equal to or greater than 10 hours;
- and
- the enonomer specifically blocks TNF-α from binding to TNFR1.
3 more elements
Dependencies are inferred from the claim text.