Multivalent carriers and related vaccine compositions
AssigneeCalifornia Institute of Technology
InventorsAlexander A. Cohen, Pamela J. Bjorkman
Life of this patent
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Abstract
Disclosed herein include multivalent carriers comprising a plurality of heterologous coronavirus proteins antigens derived from different coronaviruses. The multivalent carriers herein described can elicit heterologous binding and neutralization properties against coronaviruses that differ from the coronaviruses from which the coronavirus antigens are derived to produce the multivalent carriers. Also provided herein include vaccine compositions comprising the multivalent carriers and related methods using the vaccine compositions in various therapeutic and prophylactic applications.
Claims20
A method for treating or preventing a coronavirus infection in a subject in need thereof, comprising:
- administering to the subject a pharmaceutically effective amount of a vaccine composition, wherein the vaccine composition comprises a multivalent carrier associated with a plurality of coronavirus antigens, wherein the plurality of coronavirus antigens comprises a first coronavirus antigen of a first coronavirus and a second coronavirus antigen of a second coronavirus that is different from the first coronavirus, thereby treating or preventing the coronavirus infection in the subject.
Dependencies are inferred from the claim text.