US 2026/0074050 A1 · GENTICALLY PERSONALIZED INTRAVENOUS AND INTRAMUSCULAR NUTRITION THERAPY DESIGN SYSTEMS AND METHODS

Abstract

A method of providing genetically personalized intravenous or intramuscular nutrition therapy includes developing an initial mapping of individual micronutrients to SNPs, symptoms, conditions, and therapeutic objectives based on existing individual scientific literature references that link the specific micronutrient to an SNP, a symptom, a condition, or a therapeutic objective. The method includes receiving an SNP and a symptom, a condition, or a therapeutic objective for a patient, comparing the SNP, symptom, condition, therapeutic objective combination with the initial mapping to identify matching micronutrients, determining a nutrition therapy based on the identified micronutrients, and treating the patient accordingly. Feedback data about the nutrition therapy's effectiveness is received and the initial mapping is updated to account for the feedback data. This process is repeated for subsequent patients positioned geographically remotely from each other so that future patients are treated with reference to an updated current mapping.

A method of providing genetically personalized intravenous or intramuscular nutrition therapy, the method comprising:

developing an initial mapping of each of a plurality of individual micronutrients to a single nucleotide polymorphism (SNP) and to at least one of a symptom, a condition, and a therapeutic objective, the developing the initial mapping comprising, for each specific micronutrient of the plurality of individual micronutrients:
creating an individual score for each of a plurality of existing individual scientific literature references that links the specific micronutrient to an SNP, a symptom, a condition, or a therapeutic objective;
adding the individual scores for each of the plurality of existing individual scientific literature references for the specific micronutrient with respect to each combination of an SNP and at least one of a symptom, a condition, and a therapeutic objective;
and
determining that the specific micronutrient matches the SNP and the at least one of a symptom, a condition, and a therapeutic objective when the individual scores for the specific micronutrient with respect to the SNP and the at least one of a symptom, a condition, and a therapeutic objective add up to more than a predetermined threshold;
storing the initial mapping, the individual scores, and the added scores in a database;
receiving an SNP for a first patient and at least one of a symptom, a condition, and a therapeutic objective for the first patient;
comparing the SNP for the first patient and the at least one of a symptom, a condition, and a therapeutic objective for the first patient with the initial mapping stored in the database to identify one or more micronutrients that have been matched to the SNP for the first patient and the at least one of a symptom, a condition, and a therapeutic objective for the first patient;
determining an intravenous or intramuscular nutrition therapy for the first patient based on the identified one or more micronutrients from the initial mapping, the intravenous or intramuscular nutrition therapy comprising an existing intravenous or intramuscular nutrition therapy formula that comprises a specific dosage of at least one of the identified one or more micronutrients;
treating the first patient with the intravenous or intramuscular nutrition therapy;
receiving feedback data about an effectiveness of the intravenous or intramuscular nutrition therapy in addressing the at least one of a symptom, a condition and a therapeutic objective for the first patient;
creating an individual treatment score for the at least one of the identified one or more micronutrients in the intravenous or intramuscular nutrition therapy with respect to the SNP for the first patient and the at least one of a symptom, a condition, and a therapeutic objective for the first patient based on the feedback data;
updating the initial mapping by:
adding the individual treatment score for the at least one of the identified one or more micronutrients in the intravenous or intramuscular nutrition therapy to the added scores stored in the database that are associated with the at least one of the identified one or more micronutrients, the SNP for the first patient, and the at least one of a symptom, a condition, and a therapeutic objective for the first patient;
comparing the updated added scores with the predetermined threshold to reevaluate whether there are matches for the at least one of the identified one or more micronutrients in the intravenous or intramuscular nutrition therapy;
and
storing the updated initial mapping, the individual treatment score, and the updated added scores in the database;
and
for each of a plurality of subsequent patients positioned geographically remotely from each other:
receiving an SNP of the subsequent patient and at least one of a symptom, a condition, and a therapeutic objective of the subsequent patient;
comparing the SNP for the subsequent patient and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient with a current mapping stored in the database to identify one or more micronutrients that have been matched to the SNP for the subsequent patient and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient, wherein the current mapping has been updated with the individual treatment score of the first patient and individual treatment scores of any other previously treated patient;
determining an intravenous or intramuscular nutrition therapy for the subsequent patient based on the identified one or more micronutrients from the current mapping, the intravenous or intramuscular nutrition therapy comprising an existing intravenous or intramuscular nutrition therapy formula that comprises a specific dosage of at least one of the identified one or more micronutrients;
treating the subsequent patient with the intravenous or intramuscular nutrition therapy;
receiving feedback data about an effectiveness of the intravenous or intramuscular nutrition therapy in addressing the at least one of a symptom, a condition and a therapeutic objective for the subsequent patient;
creating an individual treatment score for the at least one of the identified one or more micronutrients in the intravenous or intramuscular nutrition therapy with respect to the SNP for the subsequent patient and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient based on the feedback data;
updating the current mapping by:
adding the individual treatment score for the at least one of the identified one or more micronutrients in the intravenous or intramuscular nutrition therapy for the subsequent patient to current added scores stored in the database that are associated with the at least one of the identified one or more micronutrients, the SNP for the subsequent patient, and the at least one of a symptom, a condition, and a therapeutic objective for the subsequent patient;
comparing the updated current added scores with the predetermined threshold to reevaluate whether there are matches for the at least one of the identified one or more micronutrients in the intravenous or intramuscular nutrition therapy for the subsequent patient;
and
storing the updated current mapping, the individual treatment score of the subsequent patient, and the updated current scores in the database;
and
treating future patients with reference to the updated current mapping.

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Gentically personalized intravenous and intramuscular nutrition therapy design systems and methods

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Gentically personalized intravenous and intramuscular nutrition therapy design systems and methods

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Abstract

Claims20