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US 2026/0069678 A1Published application
Conjugate polypeptides and vaccines for inducing immune responses
AssigneeThe Regents of the University of California
InventorDennis J. Hartigan-O'Connor
Life of this patent
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Abstract
Methods and compositions are disclosed for inducing immune responses against one or more antigens in a mammal.
Claims21
1-140. (canceled)
A method of inducing an immune response against a pathogen in a subject in need thereof, the method comprising administering a conjugate polypeptide or a recombinant nucleic acid encoding the conjugate polypeptide, wherein the conjugate polypeptide comprises:
- (a) a first peptide comprising an antigen from the pathogen;
- and
- (b) a second peptide that is capable of binding to a surface protein present on a T cell, wherein the first peptide and the second peptide are functionally linked to each other, and wherein the surface protein comprises cluster of differentiation (CD) 2, CD3, CD4, CD5, or any combination thereof.
Dependencies are inferred from the claim text.