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US 2026/0066254 A1Published application
Analytical instrument
AssigneeMicromass UK Limited
InventorsChristopher Wheeldon, Nicholas Smith, Kevin R. Howes, Ian David Trivett, Sornanathan Meyyappan, Kevin Giles
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Abstract
An analytical instrument is disclosed that comprises an ion source having a sprayer that generates a spray within an enclosure. A gas flow system causes a flow of gas through the enclosure, filters sample from the flow of gas, and senses a flow rate of the flow of gas. A controller controls the gas flow system and/or the sprayer based on the sensed flow rate.
Claims20
An analytical instrument comprising:
- an ion source comprising:
- an enclosure;
- and
- a sprayer configured to generate a spray comprising sample within the enclosure;
- a gas flow system configured to cause a flow of gas through the enclosure;
- wherein the gas flow system comprises at least one filter configured to filter sample from the flow of gas, and a flow sensor configured to sense a flow rate of the flow of gas;
- and
- a controller configured to control the gas flow system and/or the sprayer based on a flow rate sensed by the flow sensor.
5 more elements
An ion source comprising:
- an enclosure;
- a sprayer configured to generate a spray comprising sample within the enclosure;
- and
- a manifold configured to introduce a flow of gas into the enclosure as multiple different flow paths, wherein the manifold comprises a branching structure configured to split a flow of gas into the multiple different flow paths;
- wherein the branching structure is configured to split a flow of gas into the multiple different flow paths by at least splitting a parent flow path into plural child flow paths, and splitting each of the plural child flow paths into plural grandchild flow paths.
2 more elements
A method of operating an analytical instrument;
- the method comprising:
- generating ions by generating a spray comprising sample within an enclosure;
- causing a flow of gas through the enclosure;
- filtering sample from the flow of gas;
- sensing a flow rate of the flow of gas;
- and
- controlling the flow of gas and/or the generating of the spray based on the sensed flow rate.
4 more elements
Dependencies are inferred from the claim text.