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AssigneeThe Regents of the University of Michigan
InventorsAndrew Scott, Abhinav Achreja, Anjali Mittal, Deepak Nagrath, Costas A. Lyssiotis, Daniel Wahl, Baharan Meghdadi
Estimating the term…
The present disclosure relates to methods for assessing metabolic flux. In some aspects, the disclosure relates to methods for estimating absolute metabolic flux for a pathway of interest based upon a level of one or more metabolites and/or isotopologues thereof at a single point in time following administration of a tracer to a subject. In some embodiments, the methods described herein are performed or generated using artificial intelligence/machine-learning (AI/ML) models.
A method of estimating absolute metabolic flux for a metabolic pathway of interest, the method comprising:
A machine-learning method for estimating absolute activity of one or more metabolic fluxes, the method comprising:
Dependencies are inferred from the claim text.