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US 2026/0062668 A1Published application
Click chemistry ligand
AssigneeNortheastern University
InventorsSara H. Rouhanifard, Keqing Nian
Life of this patent
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Abstract
The disclosure herein provides, in example embodiments, methods and systems for labeling biomolecules with CuAAC using a copper-catalyzed azide-alkyne cycloaddition (CuAAC)-accelerating ligand.
Claims20
A system for performing Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) inside or on a surface of a cell, comprising:
- a) a CuAAC-accelerating ligand comprising a polynucleotide and one or more copper chelators;
- and
- b) a delivery reagent.
Dependencies are inferred from the claim text.