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US 2026/0062486 A1Published application
Anti-pd-1 antibodies, or fragments thereof, for treating hepatitis b
AssigneeArbutus Biopharma Corporation
InventorsChristopher Brooks MOORE, Jang-June PARK
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Abstract
Certain embodiments of the invention provide a method for treating a Hepatitis B virus infection and/or ameliorating one or more symptoms associated with a Hepatitis B virus infection in a mammal, the method comprising the step of administering to the mammal a therapeutically effective amount of an anti-PD-1 antibody, or fragment thereof.
Claims9
1-82. (canceled)
A method for treating a hepatitis B virus (HBV) infection in a human comprising administering to the human having an HBV infection a therapeutically effective amount of a combination of (i) an anti-PD-1 antibody, or fragment thereof;
- (ii) a reverse transcriptase inhibitor;
- and (iii) an oligomeric nucleotide targeted to the Hepatitis B genome.
Dependencies are inferred from the claim text.