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AssigneesPeter V. Giannoudis, Pharmaceutical Business Consultants Limited
InventorsPeter V. GIANNOUDIS, Carol O'SULLIVAN, Gerard Michael INSLEY, Paul BURKE, Regina O'SULLIVAN
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The present invention relates to an implantable device configured to deliver, to an injured bone site, components for revascularisation and bone repair, the device comprising: a first osteoconductive scaffold component adapted to hold and deliver to the injured bone site, growth factors for inducing cellular events that initiate healing; and comprising a second osteoconductive scaffold component adapted to hold and deliver to the injured bone site, viable autologous osteogenic and/or angiogenic cells, and wherein the device also comprises a third scaffold component adapted to promote bone cell proliferation and vascularity, whereby the scaffold components provide a stable mechanical environment for promoting bone cell proliferation and vascularity. The present invention also relates to a method of manufacture of the implantable device.
1-64. (canceled)
An implantable device configured to deliver components for revascularisation and bone repair to an injured bone site, the device comprising:
An implantable device for musculo-skeletal tissue healing for bone repair and regeneration and comprising a first osteoconductive scaffold component and a second osteoconductive scaffold component, wherein pores on the first osteoconductive scaffold component hold at least one Growth Factor, pores on the second osteoconductive scaffold component hold osteogenic cells and/or angiogenic cells, the implantable device further comprising an octacalcium phosphate dispersed between the first osteoconductive scaffold component and the second osteoconductive scaffold component, and
Dependencies are inferred from the claim text.