BBB interacting capsids
AssigneeuniQure biopharma B.V.
Inventors- Anggakusuma, Elena Maria Santidrian Yebra-Pimentel
Life of this patent
Estimating the term…
Abstract
The present invention relates to the fields of medicine, molecular biology, and gene therapy. In particular, the invention relates to novel recombinant adeno-associated virus capsids, uses thereof and methods of manufacturing the novel recombinant adeno-associated virus capsids.
Claims17
A recombinant adeno-associated virus (rAAV) capsid comprising a binding moiety, wherein the binding moiety confers to the rAAV capsid a phenotype of increased interaction with Transferrin receptor protein 1 (TfR1) as compared to a control rAAV capsid not comprising the binding moiety.
-16. (canceled)
Dependencies are inferred from the claim text.