Talc-free active ingredient coating

Abstract

The invention provides a dry, flowable composition in the form of a plurality of particles, each particle comprising, or consisting of, an inert starter core which is coated with at least one coat of an active ingredient composition. The particles are characterized in that the active ingredient composition is substantially free of anti-tacking agents such as talc, and the inert starter core comprises, or consists of, a sugar alcohol wherein the sugar alcohol is mannitol, in particular, a mannitol provided in a direct compression quality. The invention further provides a process for the preparation of the dry, flowable composition, and more specifically a process of coating inert starter cores with an active ingredient coat without the use of anti-tacking agents, such as talc.

Dependencies are inferred from the claim text.