Bioactive walnut peptides for treating hair loss
AssigneeL'oreal
InventorsEddy Hsi Chun WANG, Rebecca BARRESI, I-chien LIAO, Ying CHEN
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Abstract
Bioactive walnut peptides and use of the bioactive walnut peptides for topical application to the scalp are described. The bioactive walnut peptides may be incorporated into a pharmaceutical or cosmetic composition for application to the scalp. The pharmaceutical or cosmetic compositions and the one or more bioactive walnut peptides in the compositions are particularly useful for treating or preventing hair loss, and treating scalp conditions, such as dandruff, scalp psoriasis, and acne.
Claims20
A method for treating or preventing hair loss, or treating scalp conditions comprising applying to the scalp an effective amount of one or more walnut-derived peptides comprising from 2 to 20 amino acid residues and one or more amino acid sequences selected from:
- SEQ ID NO:
- 1
- (Thr-Trp),
- SEQ ID NO:
- 2
- (Trp-Leu),
- SEQ ID NO:
- 3
- (Leu-Pro),
- SEQ ID NO:
- 4
- (Pro-Leu),
- SEQ ID NO:
- 5
- (Pro-Arg),
- SEQ ID NO:
- 6
- (Tyr-Val),
- SEQ ID NO:
- 7
- (Val-Leu),
- SEQ ID NO:
- 8
- (Leu-Leu),
- SEQ ID NO:
- 9
- (Leu-Pro),
- SEQ ID NO:
- 10
- (Pro-Ser),
- SEQ ID NO:
- 11
- (Ser-Pro),
- and
- SEQ ID NO:
- 12
- (Pro-Lys).
A topical compositions for treating or preventing hair loss, or treating scalp conditions comprising:
- (a) about 0.001 to about 10 wt. % of one or more walnut-derived peptides comprising from 3 to 20 amino acid residues, provided the one or more walnut-derived peptide comprise an amino acid sequences selected from SEQ ID NOS:
- 1-46;
- (b) one or more non-walnut-derived active agents;
- and
- (c) a dermatologically acceptable carrier.
Dependencies are inferred from the claim text.