Device for Modulation of Lymphatic Clearance and Uses Thereof
AssigneeThe Texas A&M University System
InventorsSaurabh Biswas, John C. Criscione
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Abstract
Provided herein are therapeutic devices effective to modulate lymphatic clearance in a subject or patient. The therapeutic devices have a platform configured for actuation of modes of lymphatic clearance, at least one wearable sensor that senses a phase(s) of the breathing cycle, a gating apparatus to synchronize actuation with the breathing cycle as detected by the wearable sensor and a power source. Also provided are methods for modulating lymphatic clearance in a subject using the therapeutic devices.
Claims20
A therapeutic device to modulate lymphatic clearance in a subject in need thereof, comprising:
- a platform configured for actuation of at least one mode of lymphatic clearance;
- at least one wearable sensor that forms a closed feedback loop configured to sense a phase or phases of a breathing cycle in the subject;
- a gating apparatus configured to synchronize automatically the actuation of the at least one mode of lymphatic clearance to the subject's breathing cycle as obtained by the wearable sensor;
- and
- a power source operably connected to the platform, the at least one wearable sensor and the gating apparatus.
Dependencies are inferred from the claim text.