Method and system for irreversible electroporation
AssigneeCultiv8 Medical, LLC
InventorsJ. Samuel BATCHELDER, Matt HEIDNER, Jon LAWSON
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Abstract
A system for performing irreversible electroporation within a tissue under a skin surface of a patient, the system including: a power source configured to generate power; a base; and at least one electrode extending from the base, where the at least one electrode is configured to receive the power and based on the power to generate an electric field sufficient to porate a cell membrane within the tissue while increasing a temperature of the skin surface less than 3 deg C. during poration.
Claims20
A system for performing irreversible electroporation within a tissue under a skin surface of a patient, the system comprising:
- a power source configured to generate power;
- a base;
- and
- at least one electrode extending from the base, wherein the at least one electrode is configured to receive the power and based on the power to generate an electric field sufficient to porate a cell membrane within the tissue while increasing a temperature of the skin surface less than 3 deg C. during poration.
A hand-held applicator for performing irreversible electroporation within a tissue under a skin surface of a patient, the applicator comprising:
- a base;
- and
- at least one electrode extending from the base, wherein the at least one electrode is configured to generate an electric field having a maximum field strength equal to a potential difference applied to the tissue divided by a radius of curvature of a surface of the at least one electrode, while providing a treatment field of less than 0.3 times the maximum field strength a distance of 1 mm from the at least one electrode.
A method of performing irreversible electroporation within a tissue under a skin surface of a patient, the method comprising:
- applying power to at least one electrode in contact with the skin surface of the patient;
- generating with the at least one electrode, based on the applied power, an electric field, wherein the electric field is sufficient to porate a cell membrane within the tissue while increasing a temperature of the skin surface less than 3 deg C. during poration;
- and
- applying the electric field to porate the cell membrane in the tissue.
Dependencies are inferred from the claim text.