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US 2026/0055180 A1Published application
Kidney targeting antibodies
AssigneeAbdera Therapeutics Inc.
InventorsMichael J. ABRAMS, Emma Jane CUMMINS, Adam Daniel JUDGE
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Abstract
Described herein are antibodies and immunoconjugates capable of targeting antigens within the kidney. The antibodies described herein generally a polypeptide, wherein the polypeptide comprises: an antigen-binding domain (e.g., immunoglobulin single-chain domain antibody) and a Fc domain, wherein the antigen-binding domain binds an antigen present within the kidney.
Claims33
An antibody comprising:
- an antigen-binding domain and a Fc domain, wherein the antigen-binding domain binds an antigen present within the kidney, wherein the antibody possesses a molecular weight of less than 110,000 Daltons.
The method of claim 51, wherein the kidney disease or disorder is BK virus nephritis or nephropathy.
Dependencies are inferred from the claim text.