Antimicrobial polycarbonate coatings
AssigneeBoard of Regents, The University of Texas System
InventorsJoel ROSENBLATT, Issam RAAD
Life of this patent
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Abstract
Antimicrobial polycarbonate coatings are provided that may be included on the surface of a medical device such as, e.g., a needleless connector. The antimicrobial polycarbonate coatings may comprise minocycline, rifampin, and/or chlorhexidine. Methods of applying the antimicrobial polycarbonate coating to a medical device (e.g., a polycarbonate connector) are also provided.
Claims142
A medical device comprising an antimicrobial polycarbonate coating, wherein the antimicrobial coating comprises an antimicrobial agent, and polycarbonate;
- wherein the antimicrobial agent is minocycline, rifampin, or chlorhexidine;
- and wherein the antimicrobial coating and has been formed by applying a solution comprising the antimicrobial agent and the polycarbonate to a surface of the medical device and allowing the solution to dry.
The medical device of any one of claims 57-62, wherein the medical device comprises a polycarbonate layer comprises no or essentially no antimicrobial agent that is below the polycarbonate layers that contain the antimicrobial agent.
A method of producing an antimicrobial polycarbonate coating, comprising:
- (i) dissolving or dispersing an antimicrobial agent in a C1-4 alcohol, to form a first solution;
- (ii) dissolving or dispersing a polycarbonate in a solvent to form a second solution;
- (iii) mixing the first solution and the second solution to form a third solution;
- (iv) applying the third solution to a surface;
- and
- (v) substantially drying the third solution to form the antimicrobial polycarbonate coating;
- wherein the antimicrobial agent is minocycline, rifampin, or chlorhexidine.
Dependencies are inferred from the claim text.