Back to results
US 2026/0048016 A1Published application
Tamper-resistant drug dosage forms and methods of making and use thereof
AssigneeTemple University of the Commonwealth System of Higher Education
InventorReza A. Fassihi
Life of this patent
Estimating the term…
Abstract
A tamper resistant drug dosage is described. The drug dosage form includes a matrix polymer, a scaffold polymer, and a therapeutic agent, and the porosity of the drug dosage form is less than 10%. Methods for making and using the tamper resistant drug dosage forms are described.
Claims16
-10. (canceled)
A method of producing a tamper-resistant drug dosage form, the method comprising the steps of:
- providing a composition comprising a matrix polymer, a scaffold polymer, and a therapeutic agent;
- and
- compressing the composition at a pressure greater than about 40 MPa to provide a drug dosage form with a porosity less than 10%.
A method of producing a tamper-resistant drug dosage form, the method comprising the steps of:
- providing a composition comprising a matrix polymer, a scaffold polymer, and a therapeutic agent;
- feeding the composition through an extruder;
- heating the composition;
- and
- depositing the composition on a sample stage to form a tamper-resistant drug dosage form.
2 more elements
Dependencies are inferred from the claim text.