Compounds with Anti-Acinetobacter Baumannii Activity
AssigneeUniversity of Kentucky Research Foundation
InventorSylvie Garneau-Tsodikova
Life of this patent
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Abstract
The presently-disclosed subject matter provides a compound of Formula (I): or a pharmaceutically acceptable salt of the compound, wherein R1 is C1-4 alkyl, C1-4 alkene, or, wherein R3, R4, R5, and R6 are independently hydrogen or halogen, or R4 and R5, taken together with the atoms to which they are bound, form a 6-membered ring; and wherein X1 and X2 are independently C or N; and wherein R2 is or, wherein R7 and R8 are independently hydrogen, halogen, or C1-4 alkoxy; and the use thereof in controlling (Acinetobacter baumannii and treating A. baumannii infection.
Claims20
A compound having the following formula or a pharmaceutically acceptable salt thereof:
- wherein,
- R1 is C1-4 alkyl, C1-4 alkene,
- wherein
- R3, R4, R5, and R6 are independently hydrogen or halogen, or R4 and R5, taken together with the atoms to which they are bound, form a 6-membered ring;
- and
- X1 and X2 are independently C or N;
- and
- R2 is
- wherein
- R7 and R8 are independently hydrogen, halogen, or C1-4 alkoxy.
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Dependencies are inferred from the claim text.