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US 2026/0041669 A1Published application
Solid forms of a cdk inhibitor
AssigneeRelay Therapeutics, Inc.
InventorsAndre Lescarbeau, Vishnu Vardhan Reddy Karnati, Ka Ning Yip, Seema Bag, Osama Suleiman, Sanesh Mistry, Christopher Daniel Scott
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Abstract
The disclosure is in part directed to crystalline forms of (3R,5R)-5-(5-(3-(2,2-difluoroethoxy)-1-methyl-1H-pyrazole-5-carboxamido)-1H-pyrazol-3-yl)tetrahydrofuran-3-yl bicyclo[1.1.1]pentan-1-ylcarbamate, its solvates, its cocrystals, and variants thereof.
Claims27
A compound in solid form, wherein the compound is of Formula I-1:
- or a solvate thereof.
A compound of Formula (I)
- or a solvate thereof,
- wherein,
- m is 1, 2, 3, 4, 5, 6, 7, 8, or 9,
- n is 0, 0.5, 1, 1.5, 2, 2.5, or 3;
- and
- X is succinic acid, urea, nicotinamide, tartaric acid, malic acid, lactic acid, maltol, L-proline, p-toluenesulfonic acid, methane sulfonic acid, benzoic acid, or 4-aminobenzoic acid.
3 more elements
Dependencies are inferred from the claim text.