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AssigneeResearch Triangle Institute
InventorsLeah Marie JOHNSON, Ariane VAN DER STRATEN, Ginger Denison ROTHROCK, Linying Alice LI, Ellen LUECKE, Natalie GIROUARD, Zach Richard DEMKOVICH, Sai Archana KROVI
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A reservoir device comprising an active agent formulation contained within a reservoir is described. The reservoir is defined by a biodegradable, permeable polymer membrane having a thickness of at least 45 μm. The membrane allows for diffusion of an active agent of the formulation there through when positioned subcutaneously in a body of a subject.
A reservoir device comprising an active agent formulation contained within a reservoir, the reservoir defined by a biodegradable, permeable polymer membrane having a thickness of about 45 μm to about 300 μm, the membrane allowing for diffusion of an active agent of the formulation there through when positioned subcutaneously in a body of a subject.
A reservoir device comprising an active agent contained within a reservoir, the reservoir defined by a biodegradable, permeable polymer membrane, the membrane allowing for diffusion of the active agent there through with zero-order release kinetics for a time period of at least 60 days when positioned subcutaneously in a body of a subject.
A method for manufacturing a reservoir device for delivery of an active agent formulation to a subject, the method comprising:
Dependencies are inferred from the claim text.