Intravascular dual frequency sonothrombolysis mediated with microbubbles/nanodroplets

The device of claim 11 wherein the ultrasound transducer comprises a forward-viewing ultrasound transducer.

A system for sonothrombolysis mediated with contrast agents, the system comprising:

• an ultrasound transducer;
• and
• a function generator connected to the ultrasound transducer, the function generator configured for controlling application of ultrasound energy to at least one contrast agent within a blood vessel, wherein controlling the application of the ultrasound energy includes driving the ultrasound transducer with a signal having a first frequency component and a second frequency component different from the first frequency component.