Back to results
US 2026/0028667 A1Published application
Nucleotide cleavable linkers and uses thereof
AssigneeSingular Genomics Systems, Inc.
InventorsRonald Graham, Olga Adelfinskaya, Megha Cila, Rodrigo Rodriguez
Life of this patent
Estimating the term…
Abstract
Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.
Claims19
A solid support comprising
- a primer hybridized to a polynucleotide, wherein primer comprises a nucleotide having the formula:
- wherein
- B is a divalent nucleobase;
- R3A is substituted or unsubstituted alkyl, or substituted or unsubstituted heteroalkyl;
- and
- L101 is independently a bond, —NH—, —O—, —C(O)—, —C(O)NH—, —NHC(O)—, —NHC(O)NH—, —C(O)O—, —OC(O)—, substituted or unsubstituted alkylene, substituted or unsubstituted heteroalkylene, substituted or unsubstituted cycloalkylene, substituted or unsubstituted heterocycloalkylene, substituted or unsubstituted arylene, or substituted or unsubstituted heteroarylene.
3 more elements
Dependencies are inferred from the claim text.