Systems and methods for sustained relief of chronic pain

A system to provide relief of neuropathic, nociceptive, musculoskeletal, post-trauma, post-surgical, or nociplastic pain, the system comprising:

• a coiled wire percutaneous lead configured for percutaneous insertion into a portion of a body that is proximal to a region of pain;
• at least one electrode formed integrally on the lead, wherein the electrode is configured to be positioned inside the body, and at a therapeutically effective distance from a portion of at least one nerve that innervates the region of pain;
• an electrical stimulation device operatively coupled to the lead to apply electrical stimulation through the at least one electrode to at least one peripheral nerve that innervates the region of pain, to create comfortable sensations in the region of pain;
• an electrical recording device operatively coupled to the lead to record nerve and/or muscle activity in response to the electrical stimulation through the at least one electrode from at least the peripheral nerve.

A peripheral nerve stimulation system to provide relief of pain, the system comprising:

• at least one electrode placed within a therapeutically effective distance from a peripheral nerve innervating a targeted region of pain;
• and
• an electrical stimulation device delivering electrical stimulation through the at least one electrode;
• wherein the electrical stimulation comprises a waveform activating large diameter fibers in the peripheral nerve while avoiding activating large diameter peripheral nerve fibers that do not innervate the region of pain.