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AssigneeTropic Biosciences UK Limited
InventorsEyal MAORI, Yaron GALANTY, Cristina PIGNOCCHI, Angela CHAPARRO GARCIA, Ofir Meir
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A method of modifying a gene encoding or processed into a non-coding RNA molecule having no RNA silencing activity in a plant cell is disclosed. The method comprising introducing into the plant cell a DNA editing agent conferring a silencing specificity of the non-coding RNA molecule towards a target RNA of interest. A method of modifying a gene encoding or processed into a RNA silencing molecule in a plant cell is also disclosed. The method comprising introducing into the plant cell a DNA editing agent which redirects the silencing specificity of the non-coding RNA molecule towards a target RNA of interest. Plant cells, plant seeds, plants, and methods of generating plants are also disclosed.
A method of modifying a gene encoding or processed into a non-coding RNA molecule having no RNA silencing activity in a plant cell, the method comprising introducing into the plant cell a DNA editing agent conferring a silencing specificity of said non-coding RNA molecule towards a target RNA of interest, thereby modifying the gene encoding or processed into the non-coding RNA molecule.
A method of modifying a gene encoding or processed into a RNA silencing molecule to a target RNA in a plant cell, the method comprising introducing into the plant cell a DNA editing agent which redirects a silencing specificity of said RNA silencing molecule towards a second target RNA, said target RNA and said second target RNA being distinct, thereby modifying the gene encoding the RNA silencing molecule.
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A modified plant cell which is homozygous or heterozygous for a DNA editing event, wherein said DNA editing event is the modification of a gene encoding or processed into a RNA silencing molecule to a target RNA in said plant cell, using a method comprising introducing into the plant cell a DNA editing agent to generate the modification, wherein the modification redirects a silencing specificity of said RNA silencing molecule towards a second target RNA, said target RNA and said second target RNA being distinct.
Dependencies are inferred from the claim text.