Cell operation device for cell spheroids culture and analysis

Abstract

This disclosure relates to a cell operation device for the generation, culture, and collection of cellular spheroids. The device comprises a plurality of independently operable units, each including a vertically aligned first chamber and second chamber. The first chamber is configured with a microchannel and an array of through holes that enable the formation of uniform hanging drops, facilitating spheroid formation under controlled conditions. The second chamber is positioned below to receive and immobilize the spheroids for imaging or downstream processing. This modular design enables scalable and reproducible 3D cell culture suitable for biomedical research and drug screening applications.

Dependencies are inferred from the claim text.