Formulations of docetaxel
AssigneeZhuhai Beihai Biotech Co., Ltd.
InventorQun Sun
Life of this patent
Estimating the term…
Abstract
This document relates to a pharmaceutical formulation of docetaxel, or a pharmaceutically acceptable salt thereof, with two compositions that are mixed prior to being infused or administered to patients, that comprises: (a) a first liquid composition comprising docetaxel, or a pharmaceutically acceptable salt thereof, and ethanol, and (b) a second aqueous composition comprising human serum albumin and a parenterally acceptable vehicle, and wherein the said pharmaceutical formulation does not contain Polysorbate 80.
Claims7
A method for preparing a pharmaceutical formulation comprising docetaxel, or a pharmaceutically acceptable salt thereof, and human serum albumin, the method comprising:
- (i) adding a first liquid composition comprising docetaxel, or a pharmaceutically acceptable salt thereof and ethanol into an infusion bag or bottle containing a second aqueous composition comprising human serum albumin and a parenterally acceptable vehicle and (ii) inverting such infusion bag or bottle to obtain the pharmaceutical formulation;
- wherein the pharmaceutical formulation does not contain Polysorbate 80, and wherein the first liquid composition and the second aqueous composition are mixed in less than 24 hours prior to being infused or administered to patients.
Dependencies are inferred from the claim text.