Method and System for Determining a Physiological Parameter

A system (102) for a non-invasive determination of a physiological parameter, comprising:

• a first pressure cuff (150) configured to be applied to a limb of a living subject, in particular of a human being,
• a second pressure cuff (104) configured to be applied distally to the first pressure cuff to the limb of the subject,
• a inflation control unit (220) configured to inflate the first pressure cuff (150) to a pressure value exceeding a first threshold value,
• a pressure signal monitoring unit (120) configured to monitor a pressure signal of the second pressure cuff (104) after the inflation control unit (220) inflated the first pressure cuff (150),
• a deriving unit (230) configured to derive a measure indicative of mean systemic filling pressure, MSFP, from the pressure signal of the second pressure cuff (104) monitored by the pressure signal monitoring unit (120).