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US 2025/0375449 A1Published application
Pharmaceutical compositions comprising nilotinib
AssigneeXspray Pharma AB
InventorsAndreas FISCHER, Thomas ANDERSSON
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Abstract
Disclosed herein is a composition comprising: an amorphous solid dispersion (ASD) comprising nilotinib and at least one polymeric stabilizing and matrix-forming component; and at least one solid organic acid in admixture with the ASD, and uses thereof in the treatment of proliferative disorder.
Claims20
A composition comprising:
- a particulate amorphous solid dispersion (ASD) comprising nilotinib free base and copovidone;
- and
- ascorbic acid in admixture with the particulate ASD;
- wherein the ascorbic acid is present in an amount of from about 0.5 to about 5 times the amount of nilotinib (weight to weight).
1 more element
Dependencies are inferred from the claim text.