Devices and Systems For Fixating Tissue

An interventional system for fixating tissue comprising:

• a delivery system comprising:
• a delivery catheter handle having a lock control assembly,
• a delivery catheter having a first end coupled to the delivery catheter handle and a second end remote from the first end, and
• a lock line extending from the lock control assembly and through the delivery catheter;
• and
• a fixation device releasably coupled to the second end of the delivery catheter, the fixation device comprising:
• a first fixation element and a second fixation element, each of the first and second fixation elements having a first end, a free end opposite the first end, and an engagement surface therebetween for engaging tissue, the free ends being moveable between a first position and a second position,
• an actuation mechanism coupled to the first and second fixation elements, the actuation mechanism having a stud configured to move in an axial direction, wherein movement of the stud in the axial direction moves the first and second fixation elements between the first and second positions, and
• a lock comprising:
• a wedging element having a first surface and an opposing second surface, the wedging element being at least partially disposed about the stud and being moveable between a first position in which the wedging element engages the stud to arrest its movement in the axial direction, and a second position in which the wedging element is disengaged from the stud allowing the stud to move in the axial direction,
• a biasing element engaging the first surface of the wedging element and being configured to bias the wedging element toward the first position thereof, and
• a single-sided harness having a first end portion and a second end portion, the first end portion defining an opening configured to receive the lock line, and the second end portion having a foot, the foot being moveable to engage the second surface of the wedging element and move the wedging element against the bias of the biasing element from the first position to the second position of the wedging element,
• wherein the second end of the delivery catheter defines a longitudinal axis, the lock line extends through the opening of the first end portion of the single-sided harness at a first side of the longitudinal axis, and the foot of the single-sided harness is disposed at an opposite second side of the longitudinal axis.