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US 2025/0368652 A1Published application
Microbiocidal bicyclic heterocyclic carboxamide derivatives
AssigneeSyngenta Crop Protection AG
InventorsNicolas GERMAIN, Andrew EDMUNDS, Thomas James HOFFMAN, Jagadeesh Prathap KILARU, Atul MAHAJAN, Ramya RAJAN
Life of this patent
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Abstract
A compound of formula (I) wherein the substituents are as defined in claim 1, useful as pesticides, especially as fungicides.
Claims13
A compound of formula (I)
- or a stereoisomer, enantiomer, salt, or N-oxide of the compound of formula (I), wherein:
- R1 is phenyl unsubstituted or substituted with 1, 2 or 3 independently selected substituents R11;
- or
- R1 is a 5- or 6-membered monocyclic heteroaryl ring comprising 1, 2 or 3 heteroatoms each independently selected from N, O and S, wherein said heteroaryl ring is unsubstituted or substituted with 1 or 2 independently selected substituents R11;
- R11 is hydroxyl, halogen, mercapto, amino, cyano, methyl, ethyl, propyl, iso-propyl, vinyl, ethynyl, difluoromethyl, trifluoromethyl, methoxy, ethoxy, propyloxy, iso-propyloxy, tert-butoxy, propynoxy, methylsulfanyl, methylsulfonyl, difluoromethoxy, trifluoromethoxy, cyclopropyl, cyclobutyl, or cyclopropyloxy;
- Lr represents a direct bond, —O—, or —O—C(RL1A)(RL1B)—;
- wherein RL1A and RL1B are independently selected from hydrogen or methyl;
- or RL1A and RL1B together with the carbon atom to which they are attached, form a cyclopropyl;
- or
- L1 represents —NR10—(CR2R3)m—wherein R10 is selected from hydrogen or methyl;
- and m is 0 or 1;
- or
- L1 represents
- wherein # marks the bond to the nitrogen atom and the staggered line marks the bond to the group G;
- R2 and R3 are independently selected from hydrogen or methyl;
- and n is 0 or 1;
- R4 and R5 are independently selected from hydrogen, hydroxy, fluoro, methyl, cyano, or methoxy;
- or
- R4 and R5 together with the carbon atom to which they are attached, form a carbonyl, cyclopropyl, or cyclobutyl group;
- G is selected from G-1, G-2, G-3, or G-4, wherein:
- G-1 is phenyl or phenoxy, wherein said phenyl or phenoxy is unsubstituted or substituted with 1, 2 or 3 independently selected substituents RG1;
- G-2 is a 5- or 6-membered monocyclic heteroaryl or heteroaryl-oxy;
- wherein said heteroaryl comprises 1, 2 or 3 heteroatoms each independently selected from N, O and S;
- and wherein said heteroaryl is unsubstituted or substituted with 1 or 2 independently selected substituents RG2;
- G-3 is a 9- or 10-membered heterobicyclic ring system comprising 1, 2 or 3 heteroatoms each independently selected from N, O and S;
- wherein said heterobicyclic ring system is saturated, partially unsaturated, or aromatic;
- and wherein said heterobicyclic ring system is unsubstituted or substituted with 1 or 2 independently selected substituents RG3;
- G-4 is a 9- or 10-membered carbobicyclic ring system;
- wherein said carbobicyclic ring system is saturated, partially unsaturated, or aromatic;
- and wherein said carbobicyclic ring system is unsubstituted or substituted with 1 or 2 independently selected substituents RG4;
- RG1, RG2, RG3, and RG4 are independently hydroxyl, halogen, mercapto, amino, cyano, methyl, ethyl, propyl, iso-propyl, vinyl, ethynyl, difluoromethyl, trifluoromethyl, methoxy, ethoxy, propyloxy, iso-propyloxy, tert-butoxy, propynoxy, methylsulfanyl, methylsulfonyl, difluoromethoxy, trifluoromethoxy, cyclopropyl, cyclobutyl, or cyclopropyloxy;
- A is selected from A-1 to A-17:
- wherein ## marks the bond to —O—R1;
- % marks the bond to —C(O)—N(H)-L1-G;
- and
- R7, R8, R9 are independently selected from hydrogen, fluoro, chloro, bromo, iodo, methyl, ethyl, propyl, isopropyl, allyl, propargyl, cyclopropylmethyl, cyclopentyl,
- cyclohexyl, —C(═O)OCH3, —C(═O)N(CH3)2, 2-(dimethylamino)-2-oxo-ethyl, 2-(methylamino)-2-oxo-ethyl, difluoromethyl, trifluoromethyl, methylsulfonyl, methylsulfanyl, methoxy, ethoxy, cyano, hydroxyl, mercapto, or amino.
34 more elements
Dependencies are inferred from the claim text.