Polycation carrier particle
AssigneeAllarta Life Science Inc.
InventorsSamantha ROS, Mitchell Arbuthnot JOHNSON, Nicole Aliida MANGIACOTTE, Nicholas Alexander Despard BURKE, Harald Donald Helmut STOVER
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Abstract
A polycation carrier particle obtained by the polymerization of a multiacrylate monomer with one or more hydrophilic monomers to form crosslinks. The polycation carrier particle has a net positive electric charge. The multiacrylate monomer and the hydrophilic monomer(s) are as defined herein.
Claims25
A polycation carrier particle obtained by the polymerization of an acrylate monomer with one or more hydrophilic monomers to form crosslinks, wherein the polycation carrier particle has a net positive electric charge and wherein the acrylate monomer is selected from formula I or formula V
- and wherein R and R″ are each independently a hydrogen, a C1-C14 linear or branched alkyl, a C3-C8 cycloalkyl, or a 5 to 10 membered aryl or heteroaryl ring, optionally terminated by a polymerizable group, capable of crosslinking with the one or more hydrophilic monomers,
- R′ is a C2-C14 linear or branched alkyl, a C3-C8 cycloalkyl, or a 5 to 10 membered aryl or heteroaryl ring, and R′ is terminated by at least one polymerizable group, capable of crosslinking with the one or more hydrophilic monomers,
- the alkyl, cycloalkyl, aryl and heteroaryl can be optionally substituted and optionally interrupted by one or more oxygen, sulfur or nitrogen atoms, and
- R2 is C2 or C3 and wherein C3 is linear or cyclic.
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Dependencies are inferred from the claim text.