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AssigneePell Bio-Med Technology Co., Ltd.
InventorsChen-Lung Lin, Wen-Pin Chien, Hsin-Yi Wu, Li-Che Chou, Chiung-Ju Wu, Pei-Shan Yang
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Provided is a skeleton protection method, which comprises administering to a subject in need thereof an effective amount of a peptide comprising the amino acid sequence of SEQ ID NO: 1. The present invention proves that administering the peptide of SEQ ID NO: 1 can ameliorate cortical bone erosion of calcaneus bone resulting from rheumatoid arthritis (RA) and restore the decline of RA-induced bone mineral density. Therefore, the peptide of SEQ ID NO: 1 possesses a therapeutic effect for skeleton protection.
A skeleton protection method, comprising administering to a subject in need thereof an effective amount of a peptide comprising the amino acid sequence of SEQ ID NO:
A method for inhibiting proliferation of synoviocytes, comprising administering to a subject in need thereof an effective amount of a peptide comprising the amino acid sequence of SEQ ID NO:
A method for inhibiting migration of synoviocytes, comprising administering to a subject in need thereof an effective amount of a peptide comprising the amino acid sequence of SEQ ID NO:
A method for inhibiting bone resorption, comprising administering to a subject in need thereof an effective amount of a peptide comprising the amino acid sequence of SEQ ID NO:
Dependencies are inferred from the claim text.