Back to results
US 2025/0367234 A1Published application
Compositions and methods for treating pain with extracellular vesicles
OwnerMaria Ines Mitrani, Albert Mitrani +1inventors
InventorsMARIA INES MITRANI, ALBERT MITRANI, MICHAEL BELLIO
Life of this patent
Estimating the term…
Abstract
Described herein are cell-free therapeutic compositions derived from blood or plasma and uses thereof for the treatment of selected diseases and disorders.
Claims22
A method of preparing blood-derived nanoparticles, the method comprising:
- centrifuging a first amount of blood to obtain a first supernatant;
- centrifuging the first supernatant to obtain a pellet, the pellet comprising blood-derived nanoparticles;
- isolating the pellet;
- resuspending the pellet in a volume of resuspension fluid to obtain a resuspended volume;
- and
- filtering at least a portion of the resuspended volume.
3 more elements
A method of preparing blood-derived nanoparticles, the method comprising:
- centrifuging a first amount of blood to obtain a first supernatant;
- centrifuging the first supernatant to obtain a second supernatant;
- centrifuging the second supernatant to obtain a pellet, the pellet comprising blood-derived nanoparticles;
- isolating the pellet;
- resuspending the pellet in a volume of resuspension fluid to obtain a resuspended volume;
- and
- filtering at least a portion of the resuspended volume.
4 more elements
A method of preparing blood-derived nanoparticles, the method comprising:
- obtaining a first amount of blood, the first amount of blood collected from a subject;
- centrifuging the first amount of blood to obtain a first supernatant;
- obtaining a pellet, the pellet comprising blood-derived nanoparticles;
- isolating the pellet;
- resuspending the pellet in a volume of resuspension fluid to obtain a resuspended volume;
- and
- filtering at least a portion of the resuspended volume.
4 more elements
Dependencies are inferred from the claim text.