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US 2025/0320449 A1Published application
Method for Control of a Bioprocess
AssigneeCytiva Sweden AB
InventorsAndreas Axén, Helena Ohrvik, Martin Antti
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Abstract
The present invention relates to a computer implemented method (400) performed by a controller (C) configured to control a bioprocess comprised in a bioreactor (BR), the method comprising obtaining (410) measurement results by performing spectrophotometry of a bioprocessing fluid (FL), generating (420) control parameters based on the measurement results and one model and, controlling (430) the bioprocess using the generated parameters.
Claims16
A computer implemented method performed by a controller configured to control a bioprocess comprised in a bioreactor, the method comprising:
- identifying a set of bioprocessing variables contributing to a set of reference measurement results, wherein the set of bioprocessing variables comprises:
- a first subset of the set of bioprocessing variables that correspond to wanted bioprocessing variables,
- a second subset of the set of bioprocessing variables that correspond to unwanted bioprocessing variables,
- determining measurement results for a bioprocessing fluid,
- using a model to generate one or more control parameters based at least in part on the measurement results and one or more mapped phases determined based on a processing time of the bioprocess;
- and
- controlling the bioprocess using the generated one or more control parameters.
4 more elements
Dependencies are inferred from the claim text.