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US 2025/0320285 A1Published application
Albumin binding proteins and methods of use
AssigneeParagon Therapeutics, Inc.
InventorsHussam Hisham Shaheen, Yuqi Liu
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Abstract
Provided herein are albumin binding proteins and methods of making and using thereof.
Claims6
A humanized albumin binding protein comprising:
- a VHH domain, the VHH domain comprising three complementarity determining regions (CDRs), CDR1, CDR2, and CDR3 therein, wherein:
- (a) the CDR1 has an amino acid sequence represented by SEQ ID NO:
- 104;
- (b) the CDR2 has an amino acid sequence represented by SEQ ID NO:
- 141, wherein X63 is S or T;
- and
- (c) the CDR3 has an amino acid sequence represented by SEQ ID NO:
- 142, wherein X101 is T or A.
5 more elements
Dependencies are inferred from the claim text.