Amphiphilic lipid compound which contains zinc(ii)-dipicolylamine complex for nucleic acid binding and lipid nanoparticle composition comprising the same

Abstract

The present disclosure relates to an amphiphilic lipid compound which contains Zn(II)-dipicolylamine complex (Zn/DPA) for nucleic acid binding and lipid nanoparticle composition comprising the same, more specifically, the present disclosure provides an amphiphilic lipid compound for nucleic acid binding including a water-soluble linker and a hydrophobic terminal group in Zn/DPA, and a lipid nanoparticle composition including the same. By using the amphiphilic lipid compound for nucleic acid binding, it is possible to improve solubility in water and deliver nucleic acid drugs more effectively using lipid nanoparticles including the same.

Dependencies are inferred from the claim text.