Liquid crystal scaffolds and use thereof for organoid, spheroid, and 3d cellaggregate manufacturing
AssigneeThe Regents of the University of California
InventorsAmir Nasajpour, Paul S. Weiss, Ali Tamayol, Mohamadmahdi Samandari
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Abstract
The present invention provides liquid crystals and compositions thereof (e.g., liquid crystal-based scaffolds) for manufacturing various organoids, such as tumor organoids, as well as spheroids and/or 3D cell aggregates.
Claims20
A method of manufacturing a 3D cell aggregate, wherein the method comprises culturing at least one anchorage-dependent cell in the presence of a liquid crystal or a composition thereof.
A method of co-culturing at least one anchorage-dependent cell with at least one second cell, wherein the method comprises co-culturing the cells in the presence of a liquid crystal or a composition thereof.
Dependencies are inferred from the claim text.