Tonsilar organoid preparation method and use thereof
OwnerJong Man YOO, Young Chang LIM +2inventors
InventorsJong Man YOO, Young Chang LIM, Han Kyung KIM, Hye Ryeon KIM
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Abstract
The present invention relates to a tonsillar organoid preparation method and use thereof, which provides a tonsillar organoid preparation medium comprising a Hepatocyte Growth Factor (HGF) and not comprising a 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol in a Tonsil Formation Medium (TFM). This enables long-term subculture of tonsil organoids that show the same physiological activity as that of a real tonsil tissue.
Claims8
A tonsillar organoid preparation medium further comprising a Hepatocyte Growth Factor (HGF) and not comprising a 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol in a Tonsil Formation Medium (TFM).
A method for preparing tonsillar organoid comprising:
- preparing a tonsillar organoid preparation medium further comprising a Hepatocyte Growth Factor (HGF) and not comprising a 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol in a Tonsil Formation Medium (TFM);
- and
- culturing a tonsillar organoid in the tonsillar organoid preparation medium.
Dependencies are inferred from the claim text.