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AssigneeJiangsu Jibeier Pharmaceutical Co. Ltd.
InventorsXiugen WU, Zhaoguang LI, Haidao LI, Liyun NIE, Yunfeng LIU, Xu CAO, Furong WEI
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The present invention relates to the field of compound crystal forms, and particularly provides a leucogen crystalline form A, crystalline form B, a method for preparation of the crystalline form B, a pharmaceutical composition, and an application. The crystalline form A and the crystalline form B provided by the present invention have the advantages of good stability, high solubility in water, and good bioavailability.
A crystalline form A of leucogen, wherein an X-ray powder diffraction pattern of the crystalline form A shows at least three diffraction peaks at 2θ angles of 6.215°±0.2°, 9.738°±0.2°, 13.130°±0.2°, 18.072°±0.2°, 19.516°±0.2°, 21.446°±0.2°, 22.331°±0.2°, 23.688°±0.2°, and 29.390°±0.2°.
A crystalline form B of leucogen, wherein an X-ray powder diffraction pattern of the crystalline form B shows at least three diffraction peaks at 2θ angles of 8.025°±0.2°, 11.115°±0.2°, 20.310°±0.2°, 22.282°±0.2°, 28.546°±0.2°, 33.667°±0.2°, and 35.671°±0.2°.
Dependencies are inferred from the claim text.