Blood processing systems and methods

An isolation device of a blood processing system, the isolation device comprising:

• a frame;
• a blood bag neck holder mounted to the frame, the blood bag neck holder comprising an upper holder rod configured to receive a top opening of a blood bag;
• a blood bag tensioner secured to the frame, the blood bag tensioner comprising a lower holder rod configured to receive a bottom opening of a blood bag;
• and
• an isolation plate arrangement mounted to the frame and comprising a front plate and a back plate movable relative to each other,
• wherein the isolation plate arrangement is configured to at least partially house the blood bag between the front plate and the back plate when the blood bag is secured to the blood bag neck holder and the blood bag tensioner.

A cryopreparation device of a blood processing system, the cryopreparation device comprising:

• a base including a cavity stack compartment;
• a cover;
• a cavity stack compartment in an interior of the base;
• and
• a cavity stack disposed in the cavity stack compartment, the cavity stack comprising:
• a plurality of cavity plates configured to be stacked within the cavity stack compartment to seat a cryobag,
• wherein a first cavity plate on a top side of the cavity stack comprises a compartment configured to enclose the cryobag and at least one tube channel configured to receive a cryoprotectant tube, and
• wherein a second cavity plate disposed below the first cavity plate comprises a fluid pathway configured to allow the flow of a cooling fluid in the interior of the base.