A high-pressure flow-circulating hydrogen permeation test device, comprising a base, and an autoclave body and a compressor being fixedly arranged on the base, wherein a side wall of the autoclave body is fixedly provided with a sample clamp, a first end of the sample clamp is clamped with a sample and extends into an interior of the autoclave body, a second end of the sample clamp is fixedly provided with a hydrogen permeation test device, an interior of the sample clamp is communicated with the hydrogen permeation test device, the hydrogen permeation test device contains an electrolyte in contact with the sample, and a gas inlet and a gas outlet of the autoclave body are both connected with the compressor through pipelines.