Diagnostically useful results in real time

A method implemented by a system of one or more processors, the method comprising:

• obtaining a plurality of medical images of a coronary vessel tree;
• producing a first model of the coronary vessel tree based on the plurality of medical images, wherein producing the first model comprises:
• calculating resistances to flow at a plurality of locations within the coronary vessel tree;
• and
• calculating an index of vascular function at each of the plurality of locations based on the calculated resistances to flow;
• and
• producing a second model of the coronary vessel tree based on the plurality of medical images, wherein producing the second model comprises changing the first model so that one or more stenoses are absent from the coronary vessel tree.

A system comprising one or more processors and non-transitory computer storage media storing instructions that when executed by the one or more processors, cause the one or more processors to:

• obtain a plurality of medical images of a coronary vessel tree;
• produce a first model of the coronary vessel tree based on the plurality of medical images, wherein to produce the first model, the instructions cause the one or more processors to:
• calculate resistances to flow at a plurality of locations within the coronary vessel tree;
• and
• calculate an index of vascular function at each of the plurality of locations based on the calculated resistances to flow;
• and
• produce a second model of the coronary vessel tree based on the plurality of medical images, wherein producing the second model comprises changing the first model so that one or more stenoses are absent from the coronary vessel tree.

A computer-implemented method comprising:

• obtaining a plurality of medical images of a coronary vessel tree;
• determining first flow characteristics associated with the coronary vessel tree wherein individual first flow characteristics are associated with individual vessels segments which form the coronary vessel tree;
• determining an index indicative of vascular function based at least in part on the first flow characteristics;
• for a particular vessel segment, adjusting the first flow characteristic to model a healthy vessel segment without stenosis and form a second flow characteristic associated with the coronary vessel tree;
• and
• determining an adjusted index indicative of vascular function based at least in part on the second flow characteristic.

A system comprising one or more processors and non-transitory computer storage media storing instructions that when executed by the one or more processors, cause the one or more processors to:

• obtain a plurality of medical images of a coronary vessel tree;
• determine first flow characteristics associated with the coronary vessel tree wherein individual first flow characteristics are associated with individual vessels segments which form the coronary vessel tree;
• determine an index indicative of vascular function based at least in part on the first flow characteristics;
• for a particular vessel segment, adjust the first flow characteristic to model a healthy vessel segment without stenosis and form a second flow characteristic associated with the coronary vessel tree;
• and
• determine an adjusted index indicative of vascular function based at least in part on the second flow characteristic.