Devices, Systems, and Methods for Digital Microscopy

A non-transitory, computer-readable medium having instructions stored thereon, wherein the instructions, when executed by one or more processors, cause the one or more processors to perform a set of operations comprising:

• capturing, by an imaging sensor of a microscopy analyzer, one or more first images;
• determining a stain intensity;
• modifying an intensity of a light source of the microscopy analyzer, based at least in part on the determined stain intensity;
• in response to modifying the intensity of the light source, capturing one or more second images from the imaging sensor;
• inputting the one or more first images and the one or more second images into one or more machine learning models;
• identifying, via the one or more machine learning models, one or more characteristics of the one or more first images and the one or more second images;
• and
• transmitting instructions that cause a graphical user interface to display a graphical indication of the one or more characteristics of a sample.

A microscopy analyzer comprising:

• an objective lens;
• a slide;
• an imaging sensor;
• and
• a non-transitory computer-readable medium having instructions stored thereon, wherein the instructions, when executed by one or more processors, cause the one or more processors to perform a set of operations comprising:
• capturing, by an imaging sensor of the microscopy analyzer, one or more first images;
• determining a stain intensity;
• modifying an intensity of a light source of the microscopy analyzer, based at least in part on the determined stain intensity;
• in response to modifying the intensity of the light source, capturing one or more second images from the imaging sensor;
• inputting the one or more first images and the one or more second images into one or more machine learning models;
• identifying, via the one or more machine learning models, one or more characteristics of the one or more first images and the one or more second images;
• and
• transmitting instructions that cause a graphical user interface to display a graphical indication of the one or more characteristics of a sample.