Methods for immunoregulation by modulating plasminogen-apple-nematode (pan) domain-containing proteins
AssigneeUT-Battelle, LLC
InventorsWellington Muchero, Carly M. Shanks, Debjani Pal, Kuntal De
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Abstract
The present disclosure based on the inventors' recognition that PAN domain containing proteins play important immune regulating functions. Disclosed herein are methods for modulating immune responses in plants and animals, improving in vitro fertilization efficiency, and inhibiting human cell division and cellular migration in cancer cells. Also disclosed herein are genetically modified plants that are resistant to pathogenic infections.
Claims20
-7. (canceled)
A method for enhancing immune response to a pathogen in a plant comprising inactivating a gene encoding a PAN domain-containing protein in the plant.
A genetically engineered plant, wherein an endogenous gene encoding a PAN domain-containing protein has been inactivated as a result of a genetic modification.
-59. (canceled)
Dependencies are inferred from the claim text.