Ligand Operable Protein Cages
AssigneeThe Regents of the University of California
InventorsTodd Owen Yeates, Justin Miller, Eric Jinsuk Lee
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Abstract
Disclosed herein are protein cages that can be assembled and disassembled on command and methods and compositions thereof.
Claims16
A ligand operable protein cage (LOC), which comprises a plurality of subunits bound together by non-covalent interactions, wherein at least one subunit comprises a sequence that has (a) at least 90% sequence identity over a comparison window of at least X-30 consecutive amino acid residues of a subunit protein having X number of amino acid residues, said subunit protein being of a known protein cage, and (b) a given binder covalently attached to the N-terminus or the C-terminus of the at least one subunit.
Dependencies are inferred from the claim text.