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AssigneesGwangju Institute of Science and Technology, Seoul National University R&Db Foundation
InventorsYeongjae Choi, Sunghoon Kwon, Yoon Hae Koh, Woo Jin Kim, Mingweon Chon, Hansol Choi
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The polymerase chain reaction (PCR) has limitations, including a lack of efficient search strategies and inefficiencies in securing primer sequence lengths, despite its high sensitivity and specificity. Therefore, the present invention has been devised to address these issues, concerning a composition for the selection of the desired nucleic acid and a method for nucleic acid selection using it. By using the composition and method of the present invention, it becomes possible to hierarchically, efficiently, and selectively detect and amplify subsets of oligonucleotides with high specificity, which is expected to be widely utilized in the overall bio/medical field.
A method for selecting the target nucleic acid comprising a step of:
A method for selecting the target nucleic acid comprising a step of:
A composition for selecting a target nucleic acid, comprising dATP with reversible terminators, ddTTP, ddCTP, and ddGTP,
A composition for selecting a target nucleic acid, comprising dTTP with reversible terminators, ddATP, ddCTP, and ddGTP,
A composition for selecting a target nucleic acid, comprising dCTP with reversible terminators, ddATP, ddTTP, and ddGTP,
A composition for selecting a target nucleic acid, comprising dGTP with reversible terminators, ddATP, ddTTP, and ddCTP,
Dependencies are inferred from the claim text.