Freeze-drying protective agent for mesenchymal stem cell-exosomes, and application thereof

Abstract

The present disclosure belongs to the field of exosome lyophilization protection technology and discloses a freeze-drying protective agent for mesenchymal stem cell-exosomes and application thereof, which is composed of 0.1-0.2 v/v % ceramide, lysine, and 0.8-1.5 v/v % glycerol. After mixing the freeze-drying protective agent with the exosomes, a final concentration of the lysine is 50-80 mM. The freeze-drying protective agent can maintain the physical integrity of exosome, avoid exosome aggregation, and maintain the biological function of exosome, which can be used in exosome freeze-drying technology with wide application value.

Dependencies are inferred from the claim text.