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US 2025/0153178 A1Published application
Purification of nucleic acids in a microfludic chip by separation
AssigneeRevvity Health Sciences, Inc.
InventorMichael NILSSON
Life of this patent
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Abstract
A system may include a horizontal actuator to move a tray, to which a microwell plate and a microfluidic chip may be coupled. The system may include a vertical actuator to move a support arm, to which a plurality of pipettes or pipette tips may be coupled. The system may include a rotational actuator to move an angle bracket, to which a magnet may be coupled. The system may include a heater, through which the pipettes may extend. The system may include a pump to control the flow of fluids through the pipettes.
Claims7
A method, comprising:
- receiving a biological sample in a first well in a well plate;
- receiving another reagent in a second well in the well plate;
- operating a pump to draw the biological sample from the first well of the well plate into a pipette;
- operating an actuator to move the pipette from the first well of the well plate to a first well of a microfluidic chip;
- operating the pump to expel the biological sample from the pipette into the first well of the microfluidic chip;
- operating the actuator to move the pipette from the first well of the microfluidic chip to a second well of the microfluidic chip;
- operating the pump to draw the biological sample from the second well of the microfluidic chip into the pipette;
- operating the actuator to move the pipette from the second well of the microfluidic chip to the second well of the well plate;
- operating the pump to draw the other reagent from the second well of the well plate into the pipette;
- operating a heater to heat the biological sample and the other reagent within the pipette;
- operating the pump to expel the biological sample from the pipette into a third well in the well plate.
8 more elements
Dependencies are inferred from the claim text.