Fluid injector system, method of preventing fluid backflow, and computer program product

A computer program product for preventing at least a second fluid from a second fluid reservoir from flowing back into a first fluid reservoir using a fluid injector system configured to perform an injection protocol, the fluid injector system comprising a control device operatively associated with each of a first drive component configured to pressurize and inject a first fluid through a fluid conduit, and at least a second drive component configured to pressurize and inject the second fluid through the fluid conduit, the fluid conduit being in selective fluid communication with the first fluid reservoir and the second fluid reservoir, wherein the computer program product comprises non-transitory computer readable media comprising one or more instructions that, when executed by at least one processor, cause the at least one processor to:

• actuate the second drive component to pressurize and inject the second fluid through the fluid conduit;
• and
• while the second drive component is actuated, actuate the first drive component to introduce intermittent pulses of the first fluid to create a flow front interface between the first fluid and the second fluid in the fluid conduit to prevent backflow of the second fluid through the fluid conduit into the first fluid reservoir.