Imidazolate gold compounds for the treatment of lung cancer
AssigneeUniversity of Cincinnati
InventorsCristina Andreani, Caterina Bartolacci, Pier Paolo Scaglioni, Rossana Galassi, Stefania Pucciarelli
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AssigneeUniversity of Cincinnati
InventorsCristina Andreani, Caterina Bartolacci, Pier Paolo Scaglioni, Rossana Galassi, Stefania Pucciarelli
Estimating the term…
Methods of treating lung cancer in a subject in need thereof are provided, including administering to the subject an effective amount of an imidazolate gold compound according to Formula I, or a pharmaceutically acceptable salt, racemate, or enantiomer thereof: wherein R1 and R2 are independently selected from the group consisting of halo, cyano, hydroxyl, carboxyl, alkyl, aryl, esteryl, amidyl, and alkoxyl. Methods of inducing ferroptosis in a lung cancer cell and pharmaceutical compositions are also provided.
A method of treating lung cancer in a subject in need thereof, the method comprising administering to the subject an effective amount of an imidazolate gold compound according to Formula I, or a pharmaceutically acceptable salt, racemate, or enantiomer thereof:
A method of inducing ferroptosis in a lung cancer cell, the method comprising contacting the lung cancer cell with an effective amount of a compound according to Formula I, or a pharmaceutically acceptable salt, racemate, or enantiomer thereof:
18-26. (canceled)
A pharmaceutical composition for use in treating lung cancer, the composition comprising:
Dependencies are inferred from the claim text.